Humanity’s quest to halt the hands of time has been an unwavering constant throughout history, from the fountain of youth to the elixir of life. But in modern times, the narrative surrounding anti-aging and longevity has gained a profoundly scientific tilt. Traditionally, science, particularly medicine, has had the outdated approach to address the aging process by targeting the physical symptoms of it.

As research has intensified, it has become increasingly evident that the secret to robust health and longevity was hiding at the microscopic level—in cellular health.

“Aging is not just skin-deep. It's a complex process that unfolds at a molecular level,” says David Brown, Ph.D., senior scientist at Seragon Biosciences, Inc. “Consequently, understanding and addressing the biological aspects of aging are paramount to overall well-being.”

In an effort to breathe fresh life into our quest for longevity and steer the anti-aging narrative away from superficial treatment, Seragon Biosciences has launched RESTORIN.

Dr. Brown, part of the research team at Seragon, shares that RESTORIN’s groundbreaking formulation represents the culmination of years of rigorous scientific research, collaboration, and innovation, poised to redefine how we think about and approach healthy aging. The development process for which was greatly informed by the cutting-edge research and insights in the aging field, particularly those by leading experts like Dr. Nathan K. LeBrasseur.

Indeed, Seragon’s RESTORIN combines several compounds, each of which uniquely addresses cellular aging. Aging is a natural but relentless process associated with physiological decline, leading to physical frailty and reduced ability to respond to stress. One of the main drivers of this is cellular senescence, a state where cells become dysfunctional and lose their ability to divide but remain metabolically active.

“Normally, our cells have a natural mechanism to eliminate themselves when they get too old in order to make way for newer cells, but senescent cells do not. Because of this, senescent cells can build up in various parts of the body” Dr. Brown explains. In the long run this can contribute to the development of many age-related diseases. 

To combat this, RESTORIN leverages a class of compounds called senolytics. Senolytics target senescent cells, allowing them to be destroyed by the body.

Another important component to consider is NAD+. NAD+ (which stands for nicotinamide adenine dinucleotide) is a coenzyme that plays a vital role in cellular metabolism, facilitating the conversion of nutrients from the food we eat into energy that can be used by cells. As Dr. Brown explains, the older we get, the less NAD+ we have, which leads to reduced cellular energy.

To address this age-related decline in cellular NAD+, RESTORIN utilizes compounds called NAD+ precursors—which the body can easily convert into NAD+. These precursors help replenish NAD+ levels, promoting enhanced cellular energy.

That said, the science behind RESTORIN doesn’t stop here. In fact, the product also includes compounds that activate sirtuins, a family of proteins known for their role in promoting longevity by regulating a number of cellular processes, including DNA repair and responding to inflammation.

However, the effectiveness of any product depends not only on its components but also on how they are delivered and how well they are absorbed by the body. This is why RESTORIN employs SERC technology, an advanced delivery method that ensures optimal absorption. The controlled release technology is designed to release RESTORIN’s key components at a specific point in the GI tract to maximize the absorption of its active ingredients into the body.

As we unravel the mysteries of aging, companies like Seragon are set to play an increasingly central role in our quest for lifespan expansion. Rather than masking the physical symptoms of aging, RESTORIN targets aging at the cellular level, empowering people to live their best lives—at every stage of the journey.